High blood pressure medicine without side effects

Arterial hypertension is a worldwide disease, regardless of the level of development of each country. Many potential patients of a cardiologist simply do not know about their disease and continue to lead a normal life, ignoring the symptoms of a dangerous disease that slowly parasitizes throughout the body. Patients who have been diagnosed with high blood pressure sometimes do not follow the recommendations of a specialist and are also at risk of possible dangerous complications of hypertension. Only an attentive attitude to your health will not allow hypertension to unfold in full force. Moreover, modern innovative drugs for the treatment of this pathology are being developed with minimal side effects. Cough, hypotension, and syncope are extremely rare.

Etiology of hypertension

The prevalence of pathologies accompanied by high blood pressure made it possible to establish their etiology in detail over time.

The causes of high blood pressure are:

1. Hereditary weakness of the wall of the vascular bed. It causes the rapid penetration of sodium ions into its main substance, which leads to swelling of the intima, which narrows the lumen of the vessels. This phenomenon forms additional pressure, which affects the state of the whole organism.
2. Metabolic syndrome in patients causes arterial hypertension in most cases. It is manifested by obesity of abdominal predominance, a tendency to insulin resistance and the development of diabetes mellitus. This invariably affects the vessels, affects their wall and deprives it of elasticity.
3. Often, hypertension becomes a symptomatic element of somatic kidney damage or endocrine disorders in the body with damage to the adrenal glands or thyroid gland. The physiological state of pregnancy also mediates high blood pressure through a growing uterus and an increase in circulating blood.

In turn, constant high blood pressure numbers are dangerous for the heart, kidneys, organs of vision, and brain. Vessels thinned by hypertension can rupture abruptly with outflow of blood into the heart muscle or brain substance, which sometimes leads to irreparable consequences for the quality of life or even death.

It is important to familiarize each patient with the risks to his health without the necessary medications and adherence to a clear regimen for taking them. High blood pressure is a pathology that is difficult to correct with only one medication and often requires a complex of drugs. However, this does not double the impact of side effects, which is confirmed by many scientific studies. Modern drugs undergo maximum purification and many tests, which makes them harmless to humans.

At the same time, one should not overly frighten patients with dangerous complications of hypertension. Impressionable hypertensive patients sometimes do not part with a tonometer and are looking for the most effective medicines for high blood pressure. However, only a doctor can correlate all the clinical manifestations of the disease and the results of laboratory tests for competent therapy. The patient can help himself by changing his lifestyle, introducing sports into his life, reducing emotional overstrain. In combination with drug treatment, traditional medicine methods, physiotherapy methods and massage are good.

Antihypertensive drugs

Thiazide diuretics are effective diuretics. Their action is aimed at removing the water component of the blood, which reduces its specific gravity, and, consequently, the pressure on the vessels. Common hypothiazide and indapamide, when prescribed in complex therapy, can be reduced in dosage, although they practically do not cause side effects.

Beta-blockers act on receptors that are sensitive to them. They are located in the heart and blood vessels, but not all blockers act on both types of receptors. Depending on this, blockers have a vasodilating effect or not. Nebivolol, carvedilol and their analogues reduce the preload on the heart and expand the vascular bed. Metoprolol and bisoprolol only unload the heart.

Blockers are used as independent drugs for a month, but if the pressure cannot be adjusted, a drug of a different mechanism of action is added to them. Usually it becomes a diuretic or a calcium channel blocker. The main side effect of blockers is a cough that occurs in response to the narrowing of the bronchi, which have receptors for the active substances of the drugs.

One of the main mechanisms of pressure regulation is blocked by angiotensin converting enzyme inhibitors. Renin is produced by the kidneys in response to loss of vascular tone and undergoes several more changes before being converted into an enzyme that causes them to dilate. ACE inhibitors block this mechanism, reducing the workload on the heart and eliminating its hypertrophy.

Lisinopril and other tablets can also be given in the singular, but checked a month later for the need to prescribe an additional drug. The drug of this mechanism of action capoten can be used for minor pressure surges. The hypertensive crisis disappears within 15 minutes from the moment of administration of the drug.

Angiotensin II receptor blockers or sartans act on the renin-angiotensin system of pressure regulation. Losartan and other drugs of this series are long-lasting in their action and require a single dose per day. Longer-lasting drugs have also been identified: candesartan is effective for up to two days. Cough, hypotension and other side effects are not typical for all drugs affecting the renal mechanisms of pressure regulation.

Calcium blockers have also proven to be effective antihypertensive drugs. The complex mechanism of their action is associated with the formation of an action potential, in which calcium ions are directly involved. Their main effect is on the heart: not only does the pressure decrease, but the rhythm is restored and the ischemic manifestations of algia go away.

Tablets of this series are so safe that they are prescribed to pregnant women at any gestational age. Also, calcium blockers were able to replace clonidine, which was extremely popular with the past generation, who did not want to move away from it. The appointment of blockers can replace diuretics. Nifedipine fights hypertensive crises within 10 minutes when resorbed under the tongue.

Alpha-adrenergic blockers can be used in the complex therapy of hypertension due to the effect on their receptors in the heart. Innovative carvedilol is becoming the drug of choice for malignant hypertension not responding to other drug therapy.

Tablets of the central mechanism can lower the pressure. The vasoconstrictor center of the brain responds to the intake of clonidine or methyldopa by relieving not only nervous tension, but also by optimizing blood pressure. One of the side effects of this series of drugs is the emergence of dependence. But modern analogues of drugs are devoid of these negative effects. The use of obsolete drugs is permissible once.

After a diagnosis of hypertension is made, most patients receive medication without further advice. Almost every third person in the world suffers from high blood pressure, as the most common pathology of the cardiovascular system.

This determines the cost of state budgets for funds from hypertension in large quantities, which can be saved through elementary preventive measures. Even the most innovative pills do not eradicate the cause of the disease and do not bring patients closer to a complete cure. Hypertension is a disease of an unhealthy lifestyle, for which hereditary and other factors matter, but they do not play a decisive role.

Consequences of taking medication

Advances in modern medicine have made it possible to reduce the number of side effects of antihypertensive drugs to a minimum. There are pills that are safe for pregnant women, taking into account age-related changes in the elderly. However, any medicine can have negative effects due to the individual characteristics of each person.

Any individual has his own set of antigens, the intensity of the formation of the immune response, intolerance to toxins, enzymes, biologically active substances. A drug that is well tolerated by most people may not be suitable for a particular patient. Fortunately, most of the side effects are well studied, and almost all of them are listed in the annotations to the medications.

Pressure pills can provoke the following reactions in the body:

1. Diuretics, due to the removal of water, can pull along the necessary sodium and potassium ions, which provokes convulsive seizures in the legs and pain in them. Fluid excretion mediates frequent urge to urinate, and a decrease in BCC causes fatigue and decreased performance. Patients may gain weight and suffer from loss of sex drive. Cancellation or replacement of the prescribed medication quickly removes unwanted symptoms.
2. The main side effect of beta-blockers is coughing. It arises due to the fact that the tablets also act on the receptors that are sensitive to them, located not only in the heart and blood vessels, but also in the bronchi. The narrowing of the latter causes a painful cough without sputum discharge and the possibility of expectoration. The symptom disappears much earlier than the pressure builds up again and pains in the heart appear. Cough may reappear when changing body position during exercise. Blockers can also cause insomnia and depression.
3. Intermittent dry cough can also be observed with the appointment of ACE inhibitors. Other side effects include skin rash and loss of appetite. Despite the restoration of the functionality of large vessels, protection of the heart and kidneys, ACE inhibitor drugs have not shown a decrease in mortality from their clinical use with a long course. Greater efficiency was observed in diuretics.

The negative effects of tablets can be caused by their overdose. Changing the dose of a medicine can only be changed by a doctor in order to avoid unforeseen situations.

Cases of forgetfulness in patients and repeated use of the pill by mistake can provoke a cough in its usual absence, a drop in vascular tone with possible fainting, a drop in visual acuity and headaches. A single repeated dose usually does not give symptoms of poisoning and does not require detoxification therapy.

Developed countries have switched to an enhanced program for the prevention of many diseases, including hypertension. Most patients are able to control their blood pressure or at least adjust it with lifestyle changes.

Obesity and gross errors in the diet are the main causes of high blood pressure. Every citizen with any income can afford to replace his usual set of products with fresh vegetables and fruits. Sports activities are possible in any conditions, thanks to its various directions. Numerous promotions and marathons call for a healthy lifestyle.

Along with the introduction of preventive measures in medicine, the search for the ideal cure for hypertension is underway. The drugs should be used once, not cause coughing and other adverse reactions, be natural and without chemical additives. Representatives of Chinese traditional medicine are succeeding in this direction, who have invented an absolutely natural and safe antihypertensive patch.

Its effect on the body is truly unique, as it makes the whole body activate and cope with high pressure on its own.

Percutaneous penetration of the ingredients of the drug saves it from the harmful effects of digestive juices in the gastrointestinal tract.

The patch is usually installed on the skin of the abdomen near the navel, which is imperceptible under clothing and does not cause discomfort. Drugs that cause cough, hypotension, fainting can be replaced by a simple and miniature remedy. Domestic pharmacologists are also actively engaged in the search for innovative drugs for hypertension.